
Cholera
Cholera is an acute intestinal infection that can kill within hours if left untreated. Cholera is caused by ingestion of food or water contaminated with the bacterium Vibrio cholerae.(1)Key facts
- Cholera is an acute diarrheal infection caused by consuming food or water contaminated with the bacterium Vibrio cholerae.(1)
- Cholera is endemic to approximately 50 countries, primarily in South Asia, Southeast Asia, and Africa. During 2017 and 2022, cases were also reported in the Eastern Mediterranean/Middle East, the Caribbean, and the Western Pacific.(2) Since 2022, there has been a surge of cholera outbreaks worldwide.(2)
- It is estimated that every year, there are roughly 1.3 to 4.0 million cases, and 21,000 to 143,000 deaths per year worldwide due to cholera.(1)
- Symptomatic cholera is shown by watery diarrhea, vomiting and dehydration.(2)
- Although the disease often has a mild progression, without treatment Cholera can lead to death.(1,2)
- Cholera is a treatable disease.(1)
- A multifaceted approach which also includes the administration of oral cholera vaccines is key to control cholera, and to reduce deaths.(3)
- Before traveling, check possible preventive measures. The platform www.reisemedizincheck.at can help you find a travel medicine expert in your area.
What is cholera?
Cholera is an acute diarrheal infection that can kill within hours if left untreated.(1)
Cholera is caused by ingesting water or food that has been contaminated with Vibrio cholerae bacteria.(1)
In developing countries, climatological factors, namely warm air temperatures coupled with heavy rainfall (e.g., extreme weather events like hurricanes and floods) can overwhelm vulnerable sanitary infrastructure and drive incidence of epidemic cholera.(2)
Where does cholera occur?
Cholera is endemic to approximately 50 countries, primarily in South Asia, Southeast Asia, and Africa.(2)
Cholera is linked to limited access to safe water, basic sanitation facilities and poor hygiene practices.(1)
In developing countries, climatological factors, namely warm air temperatures coupled with heavy rainfall (e.g., extreme weather events like hurricanes and floods) can overwhelm vulnerable sanitary infrastructure and drive incidence of epidemic cholera.(2)
Map: Cholera risk areas with suspected and confirmed cases of cholera and watery diarrhea, January–November 2024(4)
Which travellers are at risk of contracting cholera?
Healthcare and response workers in cholera-affected areas (e.g., during an outbreak, after a disaster) also might be at increased risk for cholera.(2)
People without access to safe water or food, who do not follow handwashing recommendations, or do not use latrines or other sanitation systems are at increased risk for infection.(2)
Direct person-to-person transmission has been reported, including to healthcare workers during epidemics.(2)
What are the symptoms of cholera?
Infection is often mild or asymptomatic, but it can be severe.(2)
However, the bacteria are present in their faeces for 1-10 days after infection and are shed back into the environment, potentially infecting other people.(1)
Approximately 10% of infected people will develop severe symptoms such as watery diarrhea, vomiting, and leg cramps.(2) In these people, rapid loss of body fluids leads to dehydration and shock. Without treatment, death can occur within hours.(2)
How is cholera treated?
Rehydration is the cornerstone of cholera treatment. Oral rehydration solution and, when
necessary, intravenous fluids and electrolytes are administered.(2)
Antibiotics can reduce fluid requirements and duration of illness and are indicated in
conjunction with aggressive hydration for severe cases.(2)
With early and proper treatment, the case fatality rate should remain below 1%.(1,2)
References
- WHO. Fact sheets. Cholera. 5 December 2024. Online available: https://www.who.int/en/newsroom/fact-sheets/detail/cholera (last accessed February 2026)
- CDC. Yellow Book. Cholera. April 23,2025. Online available: https://www.cdc.gov/yellowbook/hcp/travel-associated-infections-diseases/cholera.html (last accessed February 2026)
- WHO. Launch of the renewed strategy for cholera control. 4 October 2017 – 22 March 2018. Ending Cholera – A Global Roadmap to 2030. Online available: https://www.who.int/newsroom/events/detail/2017/10/04/default-calendar/launch-of-the-renewed-strategy-for-cholera-control (last accessed February 2026)
- WHO. Multi-country outbreak of cholera, External situation report #21. December 2024. Online available:https://www.who.int/publications/m/item/multi-country-outbreak-of-cholera--externalsituation-report--21---18-december-2024 (last accessed February 2026)

